Publications
Rawal Y, Jia L, Meir A, Zhou S, Ruben EA, Kwon Y, Bernstein KA, Jasin M, Burma S, Hromas R, Mazin AV, Zhao W, Zhou D, Wasmuth EV, Greene EC, Sung P, Olsen SK
Structural insights into BCDX2 complex function in homologous recombination
Nature. 2023 doi: 10.1038/s41586-023-06219-w. PMID: 37344589.
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First publication from UT Health San Antonio Cryo-Electron Microscopy Facility!
Afsar M, Liu G, Jia L, Ruben EA, Nayak D, Sayyad Z, Bury PDS, Cano KE, Nayak A, Zhao X, Shukla A, Sung P, Wasmuth EV, Gack MU, Olsen SK
Cryo-EM structures of Uba7 reveal the molecular basis for ISG15 activation and E1-E2 thioester transfer
Nature Communications. In press.
Miyahira AK, Hawley JE, Adelaiye-Ogala R, Calais J, Nappi L, Parikh R, Seibert TM, Wasmuth EV, Wei XX, Pienta KJ, Soule HR
Exploring new frontiers in prostate cancer research
Report from the 2022 Coffey-Holden prostate cancer academy meeting
Prostate. 2023 Feb;83(3):207-226. PMID: 36443902
Yuan L, Gao F, Lv Z, Nayak D, Nayak A, Bury PDS, Cano KE, Jia L, Atligan FC, Oleinik N, Ogretmen B, El Oualid F, Wasmuth EV, Olsen SK
Structures of the bispecific Ubl activating enzyme Uba6 reveal novel catalytic and regulatory mechanisms
Nature Communications. 2022 Aug 19;13(1):4880. PMID: 35986001.
Nayak D, Wasmuth EV, Olsen SK
Clearing the air: Uniquely engaging furin as an approach to cystic fibrosis therapy
Cell Chemical Biology. 2022 June 16; 29(6): 927-929. PMID: 35714591.
Wasmuth EV*, Vanden Broeck A, LaClair JR, Hoover EA, Lawrence KE, Paknejad N, Pappas K, Matthies D, Wang B, Feng W, Watson PA, Zinder JC, Karthaus WR, de la Cruz MD, Hite RK, Manova-Todorova K, Yu Z, Weintraub ST, Klinge S, Sawyers CL*
Allosteric interactions prime androgen receptor dimerization and activation
Molecular Cell, 2022 June 2; 82(11): 2021-2031. PMID: 35447082.
Cover selection
Featured in:
Wasmuth EV, Hoover EA, Antar A, Klinge S, Chen Y, Sawyers CL
Proceedings of the National Academy of Sciences, 2020 Apr 14;117(15):8584-8592. PMID: 32220959.
Das M, Zattas D, Zinder JC, Wasmuth EV, Henri J, Lima CD
Substrate discrimination and quality control require each catalytic activity of TRAMP and the nuclear RNA exosome
Proceedings of the National Academy of Sciences, 2021 Apr 6; 118(14): e2024846118. PMID: 33782132.
Axhemi A, Wasmuth EV, Lima CD, Jankowsky E.
Substrate selectivity by the exonuclease Rrp6p
Proceedings of the National Academy of Sciences. 2019. Dec 26. pii: 201913236. PMID: 31879344.
Bose R, Karthaus WR, Armenia J, Abida W, Iaquinta PJ, Zhang Z, Wongvipat J, Wasmuth EV, Shah N, Sullivan PS, Doran MG, Wang P, Patruno A, International SU2C/PCF Prostate Cancer Dream Team, Zheng D, Schultz N, Sawyers CL
Loss of Function Mutations in ETS2 Repressor Factor (ERF) Reveal a Balance Between Positive and Negative ETS Factors Controlling Prostate Oncogenesis
Nature. 2017 Jun 29; 546(7660):671-5. PMID: 28614298.
Wasmuth EV, Zinder JC, Zattas D, Das M, Lima CD
eLife. 2017 Jul 25;6. pii: e29062. PMID: 28742025.
Wasmuth EV, Lima CD
The Rrp6 C-terminal domain binds RNA and activates the nuclear RNA exosome
Nucleic Acids Research. 2017 Jan 25; 45(2):846-60. PMID: 27899565.
Zinder JC, Wasmuth EV, Lima CD
Nuclear RNA exosome at 3.1 Å reveals substrate specificities, RNA paths, and allosteric inhibition of Rrp44
Molecular Cell. 2016 Nov 17; 64(4):734-45. PMID: 27818140.
Wasmuth EV, Januszyk K, Lima CD
Structure of an Rrp6-RNA exosome complex bound to polyA RNA
Nature. 2014 Jul 24; 511(7510):435-9. PMID: 25043052.
Wasmuth EV, Lima CD
Structure and activities of the eukaryotic RNA exosome
The Enzymes – Eukaryotic RNases and their Partners in RNA Degradation and Biogenesis. 2012; 31:53-75. PMID: 27166440.
Wasmuth EV, Lima CD
The exo- and endoribonucleolytic activities of yeast cytoplasmic and nuclear RNA exosomes are dependent on the non-catalytic core and central channel
Molecular Cell. 2012 Oct 12; 48(1):133-44. PMID: 22902556.
Yasuda K, Dawson HD, Wasmuth EV, Roneker CA, Chen C, Urban JF, Welch RM, Miller DD, Lei XG
Supplementary dietary inulin influences expression of iron and inflammation related genes in young pigs
Journal of Nutrition. 2009 Nov; 139 (11): 2018-23. PMID: 19776179.
Lindegaard ML, Wassif CA, Vaisman B, Amar M, Wasmuth EV, Shamburek R, Nielsen LB, Remaley AT, Porter FD
Characterization of placental cholesterol transport: ABCA1 is a potential target for in utero therapy of Smith-Lemli-Opitz syndrome
Human Molecular Genetics. 2008 Dec 1; 17(23):3806-13. PMID: 18775956.